ISSN: 2459-1777 | E-ISSN 2587-0394
Volume : 8 Issue : 3 Year : 2024
Could Corneal Densitometry be a Progression Criterion for Subclinical Keratoconus? [Beyoglu Eye J]
Beyoglu Eye J. 2023; 8(3): 157-165 | DOI: 10.14744/bej.2023.85688

Could Corneal Densitometry be a Progression Criterion for Subclinical Keratoconus?

Hasan Kızıltoprak1, Kemal Tekin2, Halil Ibrahim Atesoglu3, Dilara Özkoyuncu Kocabaş4, Mustafa Koç5, Mustafa Ilker Toker2
1Department of Ophthalmology, Faculty of Medicine, Adiyaman University, Adiyaman, Türkiye
2Department of Ophthalmology, Health Science University Ulucanlar Eye Training and Research Hospital, Ankara, Türkiye
3Department of Ophthalmology, Tatvan State Hospital, Bitlis, Türkiye
4Department of Ophthalmology, TOBB University, Ankara, Türkiye
5Department of Ophthalmology, Ideal Eye Center, Kayseri, Türkiye

OBJECTIVES: The objective of this study is to investigate the changes in topometry, tomography, and corneal densitometry in subclinical keratoconus (SK) at the 6-month interval.
METHODS: The clinical keratoconus and SK groups included 25 eyes; the control group included 22 eyes from 22 patients. Corneal topographic, tomographic, topometric, and densitometric values obtained using the Pentacam HR imaging system were analyzed.
RESULTS: Posterior elevation (PE), Keratoconus index (KI), index of height asymmetry (IHA), index of height decentration (IHD), Dp, Da, Final D, maximum pachymetric progression index (PPImax), and maximum Ambrósio relational thickness parameters showed significant changes between the baseline and the 6th-month follow-up in SK group (p<0.05 for all values). There were significant changes in all zones except a central layer of 6–10 zone, anterior, and central layer of 10–12 zone between the baseline and the 6th-month follow-up in the SK group (p<0.05, for all values). The changes in mean±s-tandard deviation of KI, IHA, IHD, PPImax parameters, and corneal densitometry values of the posterior layer of 0–2 mm and 2–6 mm zones were significant in the SK group compared to the controls (p<0.05, for all values).
DISCUSSION AND CONCLUSION: PE, KI, IHA, IHD, and PPImax parameters as well as increasing corneal light backscatter of the posterior central layer might be useful for follow-up of progression of SK. New multimeric parameters created by combinations of topometric, tomographic, and corneal densitometry parameters could be the future of SK follow-up.

Keywords: Densitometry, pentacam, subclinical keratoconus, tomography, topometry

Corresponding Author: Hasan Kızıltoprak, Türkiye
Manuscript Language: English
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