Beyoglu Eye J. 2020; 5(2): 102-107 | DOI: 10.14744/bej.2020.75047

Serum Vitamin D Level and Body Mass Index in Children with Vernal Keratoconjunctivitis

Gonul Karatas Durusoy¹, Yalcin Karakucuk², Beril Tulu Aygun³, Banu Solmaz^3
1Department of Ophthalmology, Dr. Ersin Arslan Training and Research Hospital, Gaziantep, Turkey
²Department of Ophthalmology, Selcuk University, Konya, Turkey
³Department of Ophthalmology, University of Health Sciences, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey

INTRODUCTION: The purpose of this study was to evaluate the body mass index (BMI) value and serum 25-hydroxyvitamin D [25(OH)D3] level in children with vernal keratoconjunctivitis (VKC).
METHODS: A total of 40 healthy, non-atopic children (control group) and 46 children with VKC (study group) were included in the study. The serum vitamin D [25(OH)D3] levels and BMI values were measured and compared between the 2 groups.
RESULTS: The mean vitamin D level measured in the healthy children (mean: 19.01±5.66 ng/mL, range: 9–33.09 ng/mL) was significantly different from the mean vitamin D level in the VKC-affected children (mean: 14.06±5.02 ng/mL, range 4.37–31 ng/mL) (p<0.001). The mean BMI in the VKC group (17.1±2.5 kg/m2) was significantly higher than the mean BMI of the healthy children (mean: 16.5±2.3 kg/m2; p=0.046). A negative correlation (Spearman’s rho=-0.275; p=0.01) was observed between the vitamin D level and the BMI value.
DISCUSSION AND CONCLUSION: The results indicated that children with VKC had a lower serum vitamin D level and a higher BMI value compared with healthy, age- and sex-matched children.

Keywords: Body mass index, correlation, serum 25 (OH)D3, vernal keratoconjunctivitis, vitamin D deficiency.

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