ISSN: 2459 - 1777 | E-ISSN 2587-0394
Volume : 6 Issue : 4 Year : 2021

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Beyoglu Eye Journal Real-Life Data of Patients with Exudative Age-Related Macular Degeneration [Beyoglu Eye J]
Beyoglu Eye J. 2021; 6(4): 304-308 | DOI: 10.14744/bej.2021.63496

Real-Life Data of Patients with Exudative Age-Related Macular Degeneration

Mesut Togaç1, Ekrem Çelik1, Evrim Polat1, Sibel Ahmet2, Ahmet Alperen Koç3, Zeynep Alkin4
1Department of Ophthalmology, Tekirdağ City Hospital, Tekirdağ, Turkey
2Department of Ophthalmology, Çatalca İlyas Çokay State Hospital, İstanbul, Turkey
3Department of Ophthalmology, Yeni Yuzyil University Faculty of Medicine, Istanbul, Turkey
4Department of Ophthalmology, Dünyagöz Hospital, İstanbul, Turkey

INTRODUCTION: The aim of this study was to examine and provide real-life data of patients with exudative-type age-related macular degeneration (AMD).
METHODS: A total of 189 eyes of 160 patients with exudative AMD treated with intravitreal anti–vascular endothelial growth factor therapy (anti-VEGF) injections (ranibizumab 0.3 mg/0.05 mL, aflibercept 2 mg/0.05 mL, bevacizumab 1.25 mg/0.05 mL) were included in the study. Patient demographic characteristics, and details of the clinical examinations, number of injections, best-corrected visual acuity (BCVA) measured with the Snellen chart, optical coherence tomography, and fundus fluorescein angiography images were evaluated at the first visit and during the follow-up period.
RESULTS: In the study group, 78 of the patients were female (48.8%) and 82 were male. The mean age was 72.20±8.97 years. While no treatment had been applied to 151 eyes before the first examination, 38 had previously received an intravitreal injection at another center. The mean number of patient visits was 5.83 in the first year, 4.68 in the second year, and 3.84 in the third year, and the mean number of injections was 4.70 in the first year, 2.08 in the second year, and 1.51 in the third year. The mean BCVA change between the first visit and the first, second, and third years was not statistically significant (p>0.05), and a significant change was observed in the mean central macular thickness (p<0.05).
DISCUSSION AND CONCLUSION: Anatomical and functional success was achieved with anti-VEGF treatment after fewer injections and visits than have been reported in randomized, controlled, clinical studies in the literature. The number of injections and visits recorded in this study was consistent with the data of other real-life studies.

Keywords: Exudative age-related macular degeneration, intravitreal injection, real-life data

Mesut Togaç, Ekrem Çelik, Evrim Polat, Sibel Ahmet, Ahmet Alperen Koç, Zeynep Alkin. Real-Life Data of Patients with Exudative Age-Related Macular Degeneration. Beyoglu Eye J. 2021; 6(4): 304-308

Corresponding Author: Mesut Togaç, Türkiye
Manuscript Language: English
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