ISSN: 2459 - 1777 | E-ISSN 2587-0394
Volume : 5 Issue : 3 Year : 2020

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Beyoglu Eye Journal Subfoveal Choroidal Thickness and Ganglion Cell Complex in Children with Type 1 Diabetes Mellitus Without Diabetic Retinopathy [Beyoglu Eye J]
Beyoglu Eye J. 2020; 5(3): 174-177 | DOI: 10.14744/bej.2020.50470

Subfoveal Choroidal Thickness and Ganglion Cell Complex in Children with Type 1 Diabetes Mellitus Without Diabetic Retinopathy

Alper Halil Bayat1, Akin Cakir1, Digdem Bezen2, Mustafa Nuri Elcioglu1
1Department of Ophthalmology, University of Health Sciences, Okmeydani Traning and Research Hospital, Istanbul, Turkey
2Department of Pediatric Endocrinology, University of Health Sciences, Okmeydani Traning and Research Hospital, Istanbul, Turkey

INTRODUCTION: This study is an analysis of the subfoveal choroidal thickness (SFCT) and ganglion cell complex (GCC) in children who have type 1 diabetes mellitus (T1D) without diabetic retinopathy.
METHODS: In all, 36 right eyes of 36 patients with T1D and 36 right eyes of sex- and age-matched healthy subjects were included in this prospective study. SFCT and GCC measurements were obtained using spectral domain optical coherence tomography (SD-OCT). Correlations between SCFT, GCC and duration of T1D, glycated hemoglobin, and age were also investigated.
RESULTS: The mean SFCT was 342.142.3 m in the T1D group and 35470.8 m in the control group (p>0.05). There was no significant difference between the groups in the GCC superior and inferior retina values. The average GCC was thinner in the T1D group (T1D group: 88.1114.93 m, control group: 103.3915.65 m; p=0.005). The mean central retinal thickness (CRT) was decreased in the T1D group (T1D group: 248.116.5 m, control group: 262.118.3 m; p=0.021).
DISCUSSION AND CONCLUSION: The mean SFCT was not significantly different in diabetic children compared with healthy eyes. The CRT and average GCC thickness were lower in children with T1D. SD-OCT can reveal neurodegenerative changes that may occur before vascular changes in diabetic children.

Keywords: Choroidal thickness, ganglion cell complex, type 1 diabetes mellitus.

Alper Halil Bayat, Akin Cakir, Digdem Bezen, Mustafa Nuri Elcioglu. Subfoveal Choroidal Thickness and Ganglion Cell Complex in Children with Type 1 Diabetes Mellitus Without Diabetic Retinopathy. Beyoglu Eye J. 2020; 5(3): 174-177

Corresponding Author: Alper Halil Bayat, Trkiye
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