ISSN: 2459-1777 | E-ISSN 2587-0394
Volume : 8 Issue : 1 Year : 2023
Beyoglu Eye Journal Evaluation of Choroidal Vascular Structure in Hyperopic Anisometropic Amblyopia [Beyoglu Eye J]
Beyoglu Eye J. 2023; 8(1): 32-37 | DOI: 10.14744/bej.2022.27870

Evaluation of Choroidal Vascular Structure in Hyperopic Anisometropic Amblyopia

Burak Ören1, Hasan Kızıltoprak1, Ferhat Önder2, Dilara Özkoyuncu Kocabaş3, Esat Yetkin1, Abdurrahman Bilen1
1Department of Ophthalmology, Faculty of Medicine, Adiyaman University, Adiyaman, Türkiye
2Department of Ophthalmology, Turhal State Hospital, Tokat, Türkiye
3Department of Ophthalmology, Faculty of Medicine, Tobb University, Ankara, Türkiye

OBJECTIVES: The aim of the study was to investigate the choroidal structure of patients with anisohypermetropic amblyopia compared to that of healthy eyes in controls of the same age.
METHODS: The study comprises three groups: One group was the amblyopic eyes of patients with anisometropic hyper-metropia (AE group), another group was the fellow eyes of patients with anisometropic hypermetropia (FE group), and a final group of healthy controls. Both the choroidal thickness (CT) and choroidal vascularity index (CVI) values were obtained using the spectral-domain optical coherence tomography (OCT) method of improved depth imaging (EDI-OCT; Heidelberg Engineering GmbH, Spectralis, Germany, Heidelberg).
RESULTS: This study included 28 anisometropic amblyopic patients (AE and FE groups) and 35 healthy controls. Regarding the distribution of ages and sexes (p=0.813 and p=0.745), the groups were the same. The mean best-corrected visual acuity in AE, FE, and the control group was 0.58±0.76, 0.008±1.30, and 0.004±1.20 logMAR units, respectively. There was a significant difference in terms of CVI, luminal area (LA), and all the CT values between groups. Post hoc univariate analyses indicated that CVI and LA were significantly higher in AE compared to FE and the control group (p<0.05, for each). The temporal, nasal, and subfoveal CT values were considerably higher in AE compared to FE and the control groups (p<0.05, for each). However, there was no difference between FE and the control group (p>0.05, for each).
DISCUSSION AND CONCLUSION: The AE group had larger LA, CVI, and CT values compared to the FE and control groups. These results show that choroidal changes in amblyopic eyes in children are permanent in adulthood if untreated and are involved in the pathogenesis of amblyopia.

Keywords: Amblyopia, Choroidal vascularity index, EDI OCT, Hyperopia.

Burak Ören, Hasan Kızıltoprak, Ferhat Önder, Dilara Özkoyuncu Kocabaş, Esat Yetkin, Abdurrahman Bilen. Evaluation of Choroidal Vascular Structure in Hyperopic Anisometropic Amblyopia. Beyoglu Eye J. 2023; 8(1): 32-37

Corresponding Author: Burak Ören, Türkiye
Manuscript Language: English
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