ISSN: 2459 - 1777 | E-ISSN 2587-0394
Volume : 2 Issue : 2 Year : 2022
Beyoglu Eye Journal Surgical Dose-Response Relationship in Patients with Down Syndrome with Esotropia: A Comparative Study [Beyoglu Eye J]
Beyoglu Eye J. 2017; 2(2): 49-52 | DOI: 10.14744/bej.2017.02419

Surgical Dose-Response Relationship in Patients with Down Syndrome with Esotropia: A Comparative Study

Osman Bulut Ocak1, Asli Inal1, Ebru Demet Aygit1, Serap Yurttaser Ocak2, Can Ozturker1, Ahmet Demirok1, Birsen Gokyigit1
1University of Health Sciences Beyoglu Eye Research and Training Hospital, Istanbul, Turkey
2University of Health Sciences Okmeydanı Research and Training Hospital, Istanbul, Turkey

INTRODUCTION: This study is a comparison of the effectiveness of bimedial rectus recession surgery in patients with Down syndrome and those with normal neurological development.
METHODS: Records of patients with Down syndrome (age range: 2-17 years) who underwent bimedial rectus recession surgery for esotropia (ET) between April 2005 and April 2016 were reviewed retrospectively. A control group was also selected from age-matched patients with normal neurological development who underwent the same surgical procedure during the period. Ocular alignment was measured with the Krimsky test. Surgical success was defined as within 10 prism diopters (PD) of orthotropia 1 year after surgery. The case and control groups were compared in terms of preoperative and postoperative esodeviation angle at 1-year follow-up, the size of the bimedial rectus recession, and postoperative surgical success.
RESULTS: A total of 21 patients with Down syndrome and 42 control subjects were included. The groups did not differ in either preoperative (Down syndrome group: 39.73±8.47 PD; control group: 37.91±7.65 PD) or postoperative near deviation angle (Down syndrome group: 5.45±11.45 PD; control group: 2.36±7.13 PD) or size of bimedial rectus recession (Down syndrome group: 4.68±0.40 mm; control group: 4.78±0.38 mm). Surgical success had been achieved in 15 patients with Down syndrome (80.90%), and in 35 control patients (83.33%) at 1-year follow-up. There was a significant difference between the preoperative and postoperative deviation angles in both groups (p<0.05).
DISCUSSION AND CONCLUSION: Surgical success rate was similar in ET patients with or without Down syndrome who underwent bimedial rectus recession surgery.

Keywords: Bimedial rectus, Down syndrome, esotropia, recession surgery.

Osman Bulut Ocak, Asli Inal, Ebru Demet Aygit, Serap Yurttaser Ocak, Can Ozturker, Ahmet Demirok, Birsen Gokyigit. Surgical Dose-Response Relationship in Patients with Down Syndrome with Esotropia: A Comparative Study. Beyoglu Eye J. 2017; 2(2): 49-52

Corresponding Author: Osman Bulut Ocak, Türkiye
Manuscript Language: English
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