ISSN: 2459-1777 | E-ISSN 2587-0394
Volume : 8 Issue : 2 Year : 2024
Comparison of the Effects of Phacoemulsıfıcatıon and Dexamethasone Implantation in the Same Session with Other Phakic Conditions [Beyoglu Eye J]
Beyoglu Eye J. 2023; 8(2): 81-90 | DOI: 10.14744/bej.2023.00922

Comparison of the Effects of Phacoemulsıfıcatıon and Dexamethasone Implantation in the Same Session with Other Phakic Conditions

Yücel Öztürk1, Ümit Çallı2, Bengi Güngör1, Esra Türkseven Kumral1, Sevcan Yildiz Balci1, Suleyman Kugu1, Nursal Melda Yenerel1
1Department of Ophthalmology, University of Health Sciences Haydarpasa Numune Training and Research Hospital, Istanbul, Türkiye
2Department of Ophthalmology, University Health Sciences, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Türkiye

OBJECTIVES: The objective of the study is to evaluate anatomical and functional results such as best corrected visual acuity (BCVA), central macular thickness (CMT), and intraocular pressure (IOP) in patients who received intravitreal dexametha-sone (DEX) implant for diabetic macular edema (DME), and to compare the efficacy according to patients’ lens status and concurrent phacoemulsification surgery.
METHODS: A total of 70 eyes of 55 patients with DME who received intravitreal DEX implantation were included in this retrospective study. Patients who received intravitreal DEX implantation were divided into three groups phaco-DEX (group 1), pseudophakic (group 2), and phakic (group 3). The BCVA, CMT, and IOP changes were compared between the three groups.
RESULTS: One month after the intravitreal DEX implant, BCVA improved in all three groups. (p=0.001, p=0.01, and p=0.009, respectively). There was a decrease in CMT at the end of 1st and 4th months in all three groups compared to the preoperative measurements (p=0.005, p<0.001, p<0.001 respectively). While IOP was increased in group 2 and group 3, no IOP increase was observed in group 1. (p=0.41, p=0.01, and p=0.01, respectively).
DISCUSSION AND CONCLUSION: Combining intravitreal DEX implantation with phacoemulsification surgery seems to be an effective and reliable method in patients with DME accompanied by cataract. The IOP elevation in follow-up visits of phakic and pseu-dophakic patients after intravitreal DEX implantation was not observed in the Phaco-DEX group.

Keywords: Cataract, diabetic macular edema, intraocular pressure, intravitreal dexamethasone.

Corresponding Author: Yücel Öztürk, Türkiye
Manuscript Language: English
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