INTRODUCTION: To evaluate the effectiveness of selective laser trabeculoplasty (SLT) to lower the intraocular pressure (IOP) as an initial or adjunctive treatment in patients with primary open-angle glaucoma (POAG).
METHODS: This is a rospective comparative study. Eighty one patients with POAG were included in this study. A total of 162 eyes of 81 patients with POAG were evaluated prospectively. Patients with bilateral POAG were included in the study. The patients were categorized into two groups. SLT was performed as an adjunctive treatment in 42 POAG patients (Group 1; 84 eyes) and as initial treatment in 39 POAG patients (Group 2; 78 eyes).
RESULTS: The mean baseline IOP and post-SLT IOP for the total number of subjects were 23.3±4.8 and 14.6±2.7 mm Hg, respectively. The mean percentage reduction of IOP post-SLT at the final visit was 34.5% in Group 1 and 40.5% in Group 2, respectively. The number of medications used in the Group 1 before the SLT was 2.11±0.88 (1-4), while after the SLT medication use decreased to 0.9 ±0.15 (0-3). Follow-up time was at 49.85±8.2 (24-78) weeks.
DISCUSSION AND CONCLUSION: Selective laser trabeculoplasty can be effectively used as a primary or an adjunctive therapy for the treatment of POAG. It was also effective in reducing the number of medications used. The reduction of IOP was similar in the primary and adjunctive group of this comparative study after up to 1 year of follow-up.