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Based on the Real-Life Data of Türkiye; Comparison of Anatomical and Functional Outcomes of Phakic and Pseudophakic Patients in Wet Type Age-Related Macular Degeneration
Havva Erdoğan Kaldırım1, Abdullah Özkaya2, Levent Karabaş3, Cengiz Alagöz4, Zeynep Alkın4, Özgür Altunay4, Sadık Etka Bayramoğlu5, Selim Bölükbaşı6, Gökhan Demir4, Mehmet Demir7, Ali Demircan4, Burak Erden6, Gürkan Erdoğan4, Mehmet Erdoğan5, Erdem Eriş4, Ismail Umut Onur8, Özen Ayrancı Osmanbaşoğlu9, Sezin Özdoğan Erkul9, Mine Özturk10, Fatma Savur1, İrfan Perente4, Kübra Sarıcı5, Nihat Sayın5, Dilek Yaşa4, İhsan Yılmaz4, Zeynep Yılmaz Abdurrahmanoğlu11Department of Ophthalmology, Bagcilar Training and Research Hospital, Istanbul, Türkiye2Department of Ophthalmology, Memorial Sisli Hospital, Istanbul, Türkiye
3Department of Ophthalmology, Kocaeli University Faculty of Medicine, Kocaeli, Türkiye
4Department of Ophthalmology, Beyoglu Eye Training and Research Hospital, Istanbul, Türkiye
5Department of Ophthalmology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Türkiye
6Department of Ophthalmology, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Türkiye
7Department of Ophthalmology, Sisli Etfal Training and Research Hospital, Istanbul, Türkiye
8Department of Ophthalmology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Türkiye
9Department of Ophthalmology, Istanbul Training and Research Hospital, Istanbul, Türkiye
10Department of Ophthalmology, Haseki Training and Research Hospital, Istanbul, Türkiye
OBJECTIVES: The aim of the study was comparison of wet-type age-related macular degeneration in phakic and pseu-dophakic patients in terms of anatomical and functional success based on the real-life data of Türkiye.
METHODS: The multicenter retrospective real-life study data of the. retinal study group were used in this study. Among 867 eyes of 867 patients were included in the study. Patients were divided into two groups according to the status of the lens; phakic group and pseudophakic group. The follow-up period of the two groups, the number of injections at the 1st, 2nd, and 3rd years, and changes in the central macular thickness (CMT, µ) and visual acuity (VA, logMAR) of the patients at the beginning, 6th, 12th, 24th, and 36th months were examined.
RESULTS: In our study, the number of injections in the 1st, 2nd, and 3rd years, respectively, was 4.2±2.0, 1.8±1.9, and 1.0±1.7 in the phakic group, and 3.9±2.0, 1.7±1.9, and 0.8±1.4 in the pseudophakic group. When the two groups were compared in terms of the number of injections, there was a statistically significant difference in the 1st year, but there was no signifi-cant difference in the 2nd and 3rd years (p=0.001, p=0.350, and p=0.288, respectively). There was no statistically significant difference between the groups in terms of CMT in the baseline, 6th, 12th, 24th, and 36th months (p=0.991, p=0.327, p=0.652, p=0.599, and p=0.873, respectively). Although there was no difference in VA between groups at the beginning (p=0.052), the phakic group showed statistically better VA in controls at 3rd, 6th, 12th, 24th, and 36th months (p=0.001, p=0.001, p=0.000, p=0.000, and p=0.003, respectively).
DISCUSSION AND CONCLUSION: Differences in the number of injections and visual results between phakic and pseudophakic patients in wet type AMD may necessitate the creation of different treatment and follow-up protocols.
Manuscript Language: English
