ISSN: 2459 - 1777 | E-ISSN 2587-0394
Subfoveal Choroidal Thickness And Ganglion Cell Complex In Children With Type 1 Diabetes Mellitus Without Diabetic Retinopathy [Beyoglu Eye J]
Beyoglu Eye J. Ahead of Print: BEJ-50470 | DOI: 10.14744/bej.2020.50470

Subfoveal Choroidal Thickness And Ganglion Cell Complex In Children With Type 1 Diabetes Mellitus Without Diabetic Retinopathy

Alper Halil Bayat1, Akin Cakir1, Diğdem Bezen2, Mustafa Nuri ELCIOGLU1
1Department of Ophthalmology, Okmeydanı Research&Traning Hospital, University of Health Sciences, İstanbul, Turkey
2Department of Pediatric Endocrinology Okmeydanı Research&Traning Hospital, University of Health Sciences, İstanbul, Turkey

INTRODUCTION: To analyze subfoveal choroidal thickness (SFCT) and ganglion cell complex (GCC) in children with type 1 diabetes mellitus (T1D) without diabetic retinopathy (DR).
METHODS: 36 right eyes of the 36 patients with T1D and 36 right eye of the sex-age-matched subjects were included in this prospective study. SFCT and GCC were obtained from spectral domain-optical coherence tomography (SD-OCT). Correlation between SCFT, GCC and duration of T1D, HbA1c, age were also investigated.
RESULTS: Mean SFCT was 342.1±42.3 µm in T1D group, 354±70.8 µm in control group (p>0.05).There was not any difference between groups in GCC superior and inferior retina. Average GGC thickness was thinner in T1D group (88.11±14.93 µm in T1D and 103.39±15.65 µm in control group, p=0.005). The mean central retinal thickness (CRT) decreased in T1D group (248.1±16.5 µm in T1D and 262.1±18.3 µm in control group p=0.021)
DISCUSSION AND CONCLUSION: The mean SFCT was not different in diabetic children and healthy eyes. CRT and average GCC thickness are decreased in T1D children. Neurodegenerative changes may occur before vascular changes in diabetic children and SD-OCT can show these changes.

Keywords: choroidal thickness, ganglion cell complex, type 1 dibetes mellitus



Corresponding Author: Alper Halil Bayat, Türkiye
LookUs & Online Makale