Primary Localized Conjunctival Amyloidosis Mimicking Lymphoma

A 27-year-old healthy male presented to our clinic with complaints of redness and burning in his left eye for the past 6 months. Biomicroscopic examination revealed a salmon-colored, elevated, painless mass lesion involving the entire lower fornix conjunctiva of the left eye. A conjunctival incisional biopsy was performed due to suspicion of lympho-proliferative disease. Histopathological examination confirmed amyloidosis. Further investigations did not reveal any evidence of systemic amyloidosis, lymphoma, or other lymphoproliferative diseases. During the 18-month follow-up after surgery, no recurrence or new findings were observed in the patient’s ophthalmologic or systemic evaluations. Amyloidosis in the periocular region can present with various clinical findings. Although a classic salmon-colored con-junctival mass initially may suggest lymphoproliferative diseases, conjunctival amyloidosis should be considered in the differential diagnosis.