INTRODUCTION: To evaluate the effects of cataract surgery on anterior segment parameters and intraocular pressure (IOP) in non-glaucomatous pseudoexfoliation syndrome (PXS) eyes.
METHODS: The cohort consisted of 65 patients on whom cataract surgery was to be performed; both with PXS (n=35) and without PXS (n=30). A complete ophthalmic examination, measurement of IOP (using applanation tonometer), and evaluation of anterior segment parameters (using Sirius Scheimpflug/Placido topography) were performed on all patients both prior, and one month post-surgery.
RESULTS: In terms of preoperative IOP, pupil diameter (PD), central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber volume (ACV), iridocorneal angle (ICA) and corneal volume (CV) values, no difference between groups was observed. A reduction in postoperative average IOP values was noted in both groups; the difference extending to slightly over 2 mmHg in the PXS group (p=0.000 in PXS group, p=0.002 in control group). Postoperatively, in terms of ACD, ICA, ACV and CV, a statistically significant increase was observed in both groups. When comparing preoperative and postoperative differences of both groups, the only parameter noted to be statistically significantly different was the postoperative widening of ICA. An increased widening was noted in the PXS group (13.83±6.06) when compared to the control group (10.47±6.69) (p=0.039).
DISCUSSION AND CONCLUSION: In our study, IOP values decreased and ACD values increased significantly following phacoemulsification in PXS and normal eyes. In terms of IOP and ACD changes our findings support the previous studies in the literature. However, an additional, previously unreported finding in this study involved ICA changes. To more fully comprehend the effects of cataract surgery on patients with PXS, in terms of ICA changes, prospective studies with a larger cohort are needed.