ISSN: 2459 - 1777 | E-ISSN 2587-0394
Volume: 4
Issue: 1
Year: 2019
Comparison of Corneal Biomechanical Properties Betweeen Physiological Macrodiscs and Glaucomatous Macrodiscs [Beyoglu Eye J]
Beyoglu Eye J. 2017; 2(1): 3-8 | DOI: 10.14744/bej.2017.21931  

Comparison of Corneal Biomechanical Properties Betweeen Physiological Macrodiscs and Glaucomatous Macrodiscs

Funda Ebru Onmez, Ayse Cigdem Altan, Banu Satana, Berna Basarir, Isıl Pasaoglu, Muhittin Taskapili
Department of Ophthalmology, Beyoglu Education and Research Hospital, Istanbul, Turkey

INTRODUCTION: This study was designed to compare optic nerve head (ONH) parameters and corneal biomechanical properties of healthy and glaucomatous macrodiscs.
METHODS: This cross-sectional study included total of 234 eyes, of which 92 served as normal controls, 92 had healthy macrodiscs, and 50 had glaucomatous macrodiscs. Measurement of ONH parameters in all p¬atients was performed using optic coherence tomography (OCT). Corneal hysteresis (CH) was measured in each patient using Ocular Response Analyzer (ORA; Reichert, Inc., Depew, NY, USA). Central corneal thickness (CCT) was determined by ultrasonic pachymetry. All OCT and ORA parameters of healthy and glaucomatous macrodiscs were compared.
RESULTS: Optic disc area of healthy macrodiscs and glaucomatous macrodiscs was similar, and larger than observed in control group (p=0.70, p=0.0001, respectively). Rim area was significantly thinner in glaucoma group than healthy macrodisc group or control group. (p=0.0001, p=0.022, respectively) Mean cup area of glaucomatous discs was larger than healthy macrodiscs (p=0.001). Cup/disc (C/D) area ratio, and horizontal and vertical C/D ratios were higher in glaucoma group than healthy macrodisc group (p=0.002, p=0.002, p=0.018, respectively) ORA analyses revealed that CH of glaucoma patients was lower than that of healthy macrodisc or control group (p=0.048, p=0.035, respectively), whereas, mean CH of macrodisc group was similar to that of control group (p=0.988). Mean CCT of macrodisc group was higher than that observed in control or glaucoma patients (p=0.015, p=0.045).
DISCUSSION AND CONCLUSION: It was concluded that OCT analyses can help differentiate healthy macrodiscs from glaucomatous discs. CH and corneal thickness measurements of healthy macrodiscs are greater than those of glaucomatous optic discs.

Keywords: ocular response analyzer, glaucoma, large optic disc, macrodisc, optic nerve head analysis


Funda Ebru Onmez, Ayse Cigdem Altan, Banu Satana, Berna Basarir, Isıl Pasaoglu, Muhittin Taskapili. Comparison of Corneal Biomechanical Properties Betweeen Physiological Macrodiscs and Glaucomatous Macrodiscs. Beyoglu Eye J. 2017; 2(1): 3-8

Corresponding Author: Funda Ebru Onmez, Türkiye


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